PWF Resources

The following published medical studies were used to help PWF develop our current hypothesis, “The Problem.”  These studies are not all focused on Pompe Disease but Lysosomal Storage Disease as a whole.  These studies will help you and your medical team see how proper diet and supplementation have been used many times with success.  PWF will continue to update these studies as more research in this area is developed.

1. Effect of a Low-Protein Diet Supplemented with Ketoacids on Skeletal Muscle Atrophy and Autophagy in Rats with Type 2 Diabetic Nephropathy

2. Improvement of Cardiomyopathy After High-Fat Diet in Two Siblings with Glycogen Storage Disease Type III

3. Ketogenic diets and physical performance

4. Ketosis may promote brain macroautophagy by activating Sirt1 and hypoxia-inducible factor-1

5. Therapeutic advances in the management of Pompe Disease and other metabolic myopathies

6. Exercise training alone or in combination with high-protein diet in patients with late-onset Pompe disease: results of a cross-over study

7. Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease.

8. Autophagy in lysosomal storage disorders

9. Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician’s Expectation Be Matched by the Reality?